The Smart Protocol
About $2,600–$3,100 in year one. The tier I ran on myself.
Problem
You want the integrated read: the full four-pillar data architecture, personalized supplementation, structured training. Without the concierge price tag. What does that actually cost — and what does it buy you?
Solution
About $2,600–$3,100 in year one. Roughly $1,000–$1,500/year ongoing.
This is the tier I ran on myself. It produced my 10-year biological-age drop. Most of the cohort participants ran at roughly this tier, adjusted for what they already owned.
| Item | One-time | Annual |
|---|---|---|
| Exome NGS (once, ever) — § 2.1 | $500 | — |
| Focused bloodwork (1–2×/year) — § 2.2 | — | $300–$600 |
| Inflammation + allergy panels (year 1, repeat every ~3 years) — § 2.3 | $300 | — |
| Wearable — Oura / Whoop / Apple (1 device, lasts ~3 years) | $400 | — |
| Universal supplement stack — § 3.1 | — | $480 |
| Personalized supplements from data — § 3.2 | — | $200–$400 |
| Gym membership or equivalent | — | $400 |
| Approximate year-one out-of-pocket | ~$2,600–$3,100 | |
| Approximate ongoing (year 2 onward) | ~$1,000–$1,500/year | |
Discussion
The integrated read is what makes this tier structurally different from § 5.1 Minimalist. You get all four data layers, you can personalize the supplement stack off specific markers, and you close the feedback loop every 90 days on bloodwork. That is the cadence the cohort experiments used.
The ongoing cost is what surprises people. Once exome and baseline inflammation are done, the annual run-rate is one bloodwork panel + the universal supplement stack + gym, plus a modest personalized stack as the data calls for it. Inflammation panels recur every three years, not annually. Personalized supplements come and go with what the data points to. Most years run well under $1,500. The expense is front-loaded, not recurring.
My own results at this tier, documented with a third-party biological-age assessment: biological age dropped 10 years; currently more than 5 years younger than chronological; all biomarkers of interest moved in the right direction; zero insurance fights; no premium clinic. Every result in § 6.1 was achieved by the cohorts running variants of this tier.
See Also
- § 5.3 · Full-Stack — what another $3–7K/year actually buys you (mostly compliance)
- § 5.4 · Start This Week — if you've decided this is the tier, here is how to start